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Immunity and disease

7 MDCAT Biology questions with answers and explanations.

All questions with answers
  1. Antibodies are produced by:

    • 1 Plasma cells
    • 2 Red blood cells
    • 3 Platelets
    • 4 Neutrophils
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    Correct answer: Plasma cells

    When B lymphocytes are activated they become plasma cells, which make large amounts of antibody.

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  2. Which blood group is the universal donor for red blood cells?

    • 1 AB positive
    • 2 O negative
    • 3 A negative
    • 4 B positive
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    Correct answer: O negative

    O negative red cells carry no A, B or Rh antigens, so they are unlikely to be attacked in the recipient.

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  3. Rhesus incompatibility can cause problems in a pregnancy when:

    • 1 The mother is Rh positive and the fetus is Rh negative
    • 2 The mother is Rh negative and the fetus is Rh positive
    • 3 Both are Rh negative
    • 4 Both are Rh positive
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    Correct answer: The mother is Rh negative and the fetus is Rh positive

    An Rh negative mother can make antibodies against the Rh antigens of an Rh positive fetus.

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  4. Which cells directly destroy virus-infected body cells?

    • 1 Cytotoxic T cells
    • 2 Plasma cells
    • 3 Mast cells
    • 4 Red blood cells
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    Correct answer: Cytotoxic T cells

    Cytotoxic T cells recognise infected cells and kill them.

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  5. Which of these is an example of passive immunity?

    • 1 Immunity after having measles
    • 2 Immunity after a vaccine
    • 3 Antibodies passed from mother to baby through breast milk
    • 4 Immunity from a booster dose
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    Correct answer: Antibodies passed from mother to baby through breast milk

    In passive immunity the antibodies are received ready-made, so the baby makes no memory cells of its own.

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  6. Malaria is caused by:

    • 1 A virus
    • 2 A bacterium
    • 3 Plasmodium, a protozoan
    • 4 A fungus
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    Correct answer: Plasmodium, a protozoan

    Plasmodium is spread by the bite of the female Anopheles mosquito.

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  7. The dengue virus is spread by:

    • 1 Anopheles mosquito
    • 2 Aedes mosquito
    • 3 House fly
    • 4 Tsetse fly
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    Correct answer: Aedes mosquito

    Dengue is carried by Aedes mosquitoes, mainly Aedes aegypti.

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